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Home Antibody All anti-FGFR1 antibodies

Anti-FGFR1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302060 Rabbit Polyclonal Antibody against FGFR1 (Y766) 100ug $325 In Stock
LC402963 FGFR1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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Also for FGFR1 (NM_023110)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenThis FGFR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-773 amino acids from human FGFR1.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman (Predicted: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000
Predicted MW Explanation 91867 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens fibroblast growth factor receptor 1 (FGFR1), transcript variant 1
Alternative NamebFGF-R-1; BFGFR; CD331; CEK; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD
Database LinkNP_075598
Entrez Gene 2260 Human
Entrez Gene 79114 Rat
FunctionFGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene can lead to Pfeiffer syndrome and Jackson-Weiss syndrome.
Related PathwayProtein KinaseTransmembraneDruggable Genome MAPK signaling pathwayAdherens junctionRegulation of actin cytoskeletonPathways in cancerProstate cancerMelanomaMore Pathways >>

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of FGFR1 (arrow) using rabbit polyclonal FGFR1 Antibody (Y766) (RB11274). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FGFR1 gene (Lane 2) (Origene Technologies).
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