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Home Antibody All anti-BFGF antibodies

Anti-BFGF TRUEMAB Antibody Clone OTI2H11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500013 bFGF (FGF2) mouse monoclonal antibody, clone OTI2H11 (formerly 2H11) 100ul $325 In Stock
LC400733 FGF2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500013 Carrier-free (BSA/glycerol-free) BFGF mouse monoclonal antibody, clone OTI2H11 (formerly 2H11) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 10-155 of human bFGF (NP_001997) produced in E.coli.
Clone NameClone OTI2H11 IsotypeIgG1
Species ReactivityHuman Concentration0.3 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:5000~10000,
Predicted MW Explanation 30.6 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens fibroblast growth factor 2 (basic) (FGF2)
Alternative NameBFGF; FGF-2; FGFB; HBGF-2
Database LinkNP_001997
Entrez Gene 2247 Human
FunctionBFGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Related PathwaySecreted ProteinDruggable Genome MAPK signaling pathwayRegulation of actin cytoskeletonPathways in cancerMelanoma

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BFGF (RC217426, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BFGF.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-BFGF monoclonal antibody.
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BFGF antibody (2H11) at 1:10000 + Recombinant human bFGF (Cat# RC217426)
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