Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
Homo sapiens Fc fragment of IgE, low affinity II, receptor for (CD23) (FCER2), transcript variant 1
Synonyms:
BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF
Immunogen
A synthetic peptide corresponding to residues near the C-terminus (extracellular domain) of human CD23. This antibody can recognize both membrane-bound and soluble forms of CD23.
Buffer
Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
CD23 is a type II transmembrane glycoprotein which functions as a receptor for IgE. CD23 is involved in the regulation of IgE production and in the differentiation of B-cells. It is expressed in many haemopoietic cell types CD21 has been identified as a ligand for CD23 in the control of IgE production (1). CD23 expression has been detected in neoplastic cells from B cell chronic lymphocyctic leukaemia and in some centroblastic/centrocytic lymphoma cases. CD23 staining is used in the differentiation of small lymphocytic lymphomas and mantle cell lymphoma (2).
Related Pathway
Hematopoietic cell lineage
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