Home Antibody All anti-FBN2 antibodies
Anti-FBN2 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for FBN2 (NM_001999)
|DNA immunization. This antibody is specific for the N Terminus Region of the target protein.|
|ELISA, IHC, IF
||WB: 1:500; ELISA: 1:100-1:2000; IHC: 1:100; IF: 1:25
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens fibrillin 2 (FBN2)|
|Fibrillin 2 is a member of the Fibrillin family of structural proteins found in the 10-12 nm extracellular calcium-binding microfibrils. These microfibrils can be found in association with elastin or in elastin-free bundles. Fibrillin-2-containing microfibrils regulate the early process of elastic fiber assembly. Defects in FBN2 are associated with congenital contractural arachnodactyly (CCA), also known as Beals syndrome.|
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Immunohistochemical staining of human heart muscle shows distinct cytoplasmic positivity in myocytes.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
Immunofluorescent staining of human cell line U-2 OS shows positivity in cytoplasm.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.