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Home Antibody All anti-FBLN5 antibodies

Anti-FBLN5 Antibody EPR685

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307164
  • Rabbit monoclonal antibody against Fibulin-5(clone EPR685)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401904) , 20ug
100ul 325 In Stock
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WB(1)
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Also for FBLN5 (NM_006329)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Fibulin-5 was used as an immunogen.
Clone NameEPR685 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
Purification Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens fibulin 5 (FBLN5)
Alternative NameADCL2; ARCL1A; ARMD3; DANCE; EVEC; FIBL-5; UP50
Database LinkNP_006320
FunctionFibulin-5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries, but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, Fibulin-5 may play a role in vascular development and remodeling. Defects in Fibulin-5 are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3) (1).
Related Pathway

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WB Image
Western blot - Anti-Fibulin 5 antibody [EPR685]; All lanes : Anti-Fibulin 5 antibody [EPR685] at 1/1000 dilution.Lane 1 : A431 cell lysate.Lane 2 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 50 kDa.

 

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