This gene encodes a cancer-testis antigen that is highly expressed in hepatocellular carcinomas and other tumors and weakly expressed in normal tissues except testis. The protein is strongly expressed in spermatogonia, primary spermatocytes, and Sertoli cells in seminiferous tubules. This protein may have a role in the control of early testicular differentiation and cell proliferation. [provided by RefSeq]. COMPLETENESS: full length.
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FATE1 (RC205951, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FATE1.
HEK293T cells transfected with either RC205951 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-FATE1 antibody(TA505183), and then analyzed by flow cytometry.
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