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Anti-FANCD2 Antibody EPR2302
Also for FANCD2 (NM_001018115)
|A synthetic peptide corresponding to residues in human FANCD2 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC/IF: 1:250 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens Fanconi anemia, complementation group D2 (FANCD2), transcript variant 2|
|FA-D2; FA4; FACD; FAD; FAD2; FANCD|
Entrez Gene 2177 Human
Entrez Gene 211651 Mouse
Entrez Gene 312641 Rat
|The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group, FANCH, is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. FANCD2 is also known as Fanconi anemia group D2 protein. It is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair.|
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Western blot - FANCD2 antibody [EPR2302]; All lanes : Anti-FANCD2 antibody [EPR2302] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : SKBR-3 cell lysate.Lane 4 : K562 cell lysate.Lane 5 : HL60 cell lysate.Lane 6 : C6 cell lysate.Lane 7 : PC-12 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 166 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FANCD2 antibody [EPR2302]; Immunohistochemical staining of paraffin-embedded Human tonsil tissue using TA307630 at a dilution of 1/100.
Immunocytochemistry/ Immunofluorescence - FANCD2 antibody [EPR2302]; Immunofluorescent staining of HeLa cells using TA307630 at a dilution of 1/250.