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Home Antibody All anti-FANCA antibodies

Anti-FANCA Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308599
  • Rabbit polyclonal antibody to FACA (Fanconi anemia, complementation group A)
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 220 of FANCA (Uniprot ID#O15360)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 33kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens Fanconi anemia, complementation group A (FANCA), transcript variant 1
Alternative NameFA; FA-H; FA1; FAA; FACA; FAH; FANCH
Database LinkNP_000126
Entrez Gene 2175 Human
FunctionThe Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: A431 . B: Hela. 12% SDS PAGE. TA308599 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded OV90 xenograft, using FACA(TA308599) antibody at 1:500 dilution.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using FACA(TA308599) antibody at 1:200 dilution.

 

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