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Home Antibody All anti-FAIM2 antibodies

Anti-FAIM2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306043
  • Rabbit Polyclonal LFG Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415867) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for FAIM2 (NM_012306)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenLFG antibody was raised against a 16 amino acid peptide from near the amino terminus of human LFG .
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens Fas apoptotic inhibitory molecule 2 (FAIM2)
Alternative NameLFG; LFG2; NGP35; NMP35; TMBIM2
Database LinkNP_036438
Entrez Gene 23017 Human
Entrez Gene 72393 Mouse
Entrez Gene 246274 Rat
FunctionProgrammed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. LFG is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-? death signal. In this respect, LFG is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. LFG, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. LFG is widely distributed, but highly expressed in the hippocampus and other neural tissues. LFG was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LFG in EL4 cell lysate with LFG antibody at (A) 0.5 and (B) 1 ug/ml.
IHC Image
Immunohistochemistry of LFG in mouse brain tissue with LFG antibody at 5 ug/ml.

 

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