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Home Antibody All anti-F11R antibodies

Anti-F11R Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA305723 Goat Anti-F11R / JAM-A Antibody 100ug $325 3-7 Days
LC429529 F11R HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-QPSARSEGEFKQTS, from the C-Terminus of the protein sequence according to NP_058642.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.3-2ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens F11 receptor (F11R)
Alternative NameCD321; JAM; JAM1; JAMA; JCAM; KAT; PAM-1
Database LinkNP_058642
Entrez Gene 50848 Human
Entrez Gene 16456 Mouse
Entrez Gene 116479 Rat
Entrez Gene 478974 Dog
FunctionTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Tight junctionLeukocyte transendothelial migrationEpithelial cell signaling in Helicobacter pylori infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA305723 (0.3ug/ml) staining of Human Peripheral Blood Mononucleocyte lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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