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Anti-EZH2 TRUEMAB Antibody Clone OTI2B10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA802907 EZH2 mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) 100ul $325 In Stock
LC401416 EZH2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF802907 Carrier-free (BSA/glycerol-free) EZH2 mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) 100ug $450 3-4 Days
Conjugation is available for this antibody: choose conjugation type

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(3)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 182-431 of human EZH2 ( NP_004447) produced in E.coli.
Clone NameClone OTI2B10 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 85.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens enhancer of zeste homolog 2 (Drosophila) (EZH2), transcript variant 1
Alternative NameENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2
Database LinkNP_004447
Entrez Gene 2146 Human
FunctionThis gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EZH2 (RC202054, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EZH2.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-EZH2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH9.0, 120C for 3min, TA802907)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-EZH2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH9.0, 120C for 3min, TA802907)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-EZH2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH9.0, 120C for 3min, TA802907)
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