Home Antibody All anti-EZH2 antibodies
Anti-EZH2 Antibody Polyclonal
Also for EZH2 (NM_001203247)
|EZH2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human EZH2.|
||WB: 1 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
|EZH2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|EZH2 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens enhancer of zeste homolog 2 (Drosophila) (EZH2), transcript variant 3|
|ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2|
Entrez Gene 2146 Human
Entrez Gene 14056 Mouse
|EZH2 Antibody: EZH2 was initially identified as a homolog of the drosophila Enhancer of Zeste through exon trap screening of chromosome 21. Both EZH2 and the related protein EZH1 can form complexes with the noncanonical Polycomb repressive complex-2 (PRC2) and maintain repressive chromatin, but the PRC2-EZH1 complex mediates methylation of histone H3. Both EZH1 and EZH2 are thought to function in the maintenance of embryonic stem cell pluripotency and plasticity and recently have been shown to be essential for hair follicle homeostasis and wound repair. Overexpression of EZH2 has been reported as a marker for advanced and metastatic cancers. |
|Transcription FactorsDruggable Genome |
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Western blot analysis of EZH2 in 293 cell lysate with EZH2 antibody at 1 ug/mL.
Immunofluorescence of EZH2 in 293 cells with EZH2 antibody at 20 ug/mL.