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Anti-ETS1 Antibody EPR546(2)
Also for ETS1 (NM_005238)
|A synthetic peptide corresponding to residues in human ETS1 was used as an immunogen.|
||Tissue culture supernatant
|Mouse, Human (Does not react with: Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog 1 (ETS1), transcript variant 2|
|ETS-1; EWSR2; p54|
Entrez Gene 2113 Human
Entrez Gene 23871 Mouse
|ETS transcriptions factors, such as ETS1, regulate numerous proteins and are involved in stem cell development, cell senescence and death, and tumorigenesis (1). Furthermore, it regulates the expression of several angiogenic and extracellular matrix remodeling factors promoting an invasive phenotype (2). The conserved ETS domain within ETS1 is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target proteins (2). ETS-1 is expressed in a variety of cells, including endothelial cells, vascular smooth muscle cells and epithelial cells (2).|
|Transcription FactorsDruggable Genome Dorso-ventral axis formationPathways in cancerRenal cell carcinoma|
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Western blot - ETS1 antibody [EPR546(2)]; All lanes : Anti-ETS1 antibody [EPR546(2)] at 1/1000 dilution.Lane 1 : MCF-7 cell lysate.Lane 2 : Daudi cell lysate.Lane 3 : Molt-4 cell lysate.Lane 4 : PBMC lysate.Lane 5 : HepG2 cell lysate.Lane 6 : Jurkat cell lysate.Lane 7 : Saos-2 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 50 kDa.