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Home Antibody All anti-ESX1 antibodies

Anti-ESX1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306921
  • Rabbit Polyclonal ESX1 Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenESX1 antibody was raised against a 19 amino acid peptide near the center of human ESX1.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens ESX homeobox 1 (ESX1)
Alternative NameESX1L; ESXR1
Database LinkNP_703149
Entrez Gene 80712 Human
FunctionHomeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of ESX1 in human testis tissue lysate with ESX1 antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of ESX1 in human testis tissue with ESX1 antibody at 2.5 ug/mL.
IF Image
Immunofluorescence of ESX1 in human testis tissue with ESX1 antibody at 20 ug/mL.

 

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