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Home Antibody All anti-ESR1 antibodies

Anti-ESR1 Antibody

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SKU Description Amount Price Availability*  
TA321068 Anti-ESR1 Rabbit Polyclonal Antibody 100ul $325 2-3 Weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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IHC(2)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 247-261 amino acids of Human estrogen receptor 1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration3.1mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:1000-10000, IHC: 1:100-300
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens estrogen receptor 1 (ESR1), transcript variant 1
Alternative NameER; Era; ESR; ESRA; ESTRR; NR3A1
Database LinkNP_000116
Entrez Gene 2099 Human
Entrez Gene 13982 Mouse
Entrez Gene 24890 Rat
FunctionThis gene encodes an estrogen receptor; a ligand-activated transcription factor composed of several domains important for hormone binding; DNA binding; and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function; but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer; endometrial cancer; and osteoporosis. Alternative splicing results in several transcript variants; which differ in their 5' UTRs and use different promoters.
Related PathwayNuclear Hormone ReceptorTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Predicted cell location: Cytoplasm, Nucleus. Positive control: Human brain and thyroid cancer tissue. Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded Human brain and thyroid cancer tissue using ESR1 antibody at dilution 1/76, on the right is treated with the synthetic peptide. (Original magnification:x200)
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Predicted cell location: Cytoplasm, Nucleus. Positive control: Human brain and thyroid cancer tissue. Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded Human brain and thyroid cancer tissue using ESR1 antibody at dilution 1/76, on the right is treated with the synthetic peptide. (Original magnification:x200)
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