The protein encoded by this gene is a cell surface transmembrane protein that may act as an erythroid cell receptor,possibly as a mediator of cell adhesion. Polymorphisms in this gene are responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene.
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HEK293T cells transfected with either pCMV6-ENTRY ERMAP(RC215022)(Red) or empty vector control plasmid(Blue) were immunostained with anti-ERMAP mouse monoclonal(TA500911), and then analyzed by flow cytometry.
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