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Anti-ERG TRUEMAB Antibody Clone OTI8A9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506201 ERG mouse monoclonal antibody, clone OTI8A9 (formerly 8A9) 100ul $325 In Stock
LC403650 ERG HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506201 Carrier-free (BSA/glycerol-free) ERG mouse monoclonal antibody, clone OTI8A9 (formerly 8A9) 100ug $450 8-10 Days
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WB(2)
IHC(1)
IF(2)

OriGene Data

ImmunogenFull lengthu human recombinant protein of human ERG(NP_891548) produced in HEK293T cell.
Clone NameClone OTI8A9 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:4000, IHC: 1:150, IF: 1:50-1:100
Predicted MW Explanation 53.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog (ERG), transcript variant 1
Alternative Nameerg-3; p55
Database LinkNP_891548
Entrez Gene 2078 Human
FunctionThis gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ERG (RC208093, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ERG.
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Western blot analysis of extracts (10ug) from 2 different cell lines by using anti-ERG monoclonal antibody.(1:200)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-ERG mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506201)
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Anti-ERG mouse monoclonal antibody (TA506201) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ERG(RC208093) at 1:100
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Immunofluorescent staining of HeLa cells using anti-ERG mouse monoclonal antibody (TA506201) at 1:100
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