OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-ERG antibodies

Anti-ERG Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323881
  • Anti-ERG Rabbit Polyclonal Antibody
100ul $325 2-3 Weeks
Add to Shopping Cart
IHC(2)
spacer
Also for ERG (NM_004449)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from N terminal 150 amino acids of human v-ets erythroblastosis virus E26 oncogene homolog (avian)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:2000-5000, IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog (ERG), transcript variant 2
Alternative Nameerg-3; p55
Database LinkNP_004440
FunctionThis gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development; cell proliferation; differentiation; angiogenesis; inflammation; and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium; inducing vascular cell remodeling. It also regulates hematopoesis; and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations; resulting in different fusion gene products; such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer; EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cytoplasm. Positive control: Human gastric and lung cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using ERG antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification:x 200)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human gastric and lung cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human lung cancer tissue using ERG antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification:x200)

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title