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Home Antibody All anti-ERCC8 antibodies

Anti-ERCC8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308479
  • Rabbit polyclonal antibody to CSA (excision repair cross-complementing rodent repair deficiency, complementation group 8)
100ul 325 3-7 Days
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WB(2)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 106 and 330 of CSA (Uniprot ID#Q13216)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.94mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000; Functional:Assay:
Predicted MW Explanation 44kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens excision repair cross-complementation group 8 (ERCC8), transcript variant 2
Alternative NameCKN1; CSA; UVSS2
Database LinkNP_001007234
Entrez Gene 1161 Human
Entrez Gene 71991 Mouse
FunctionThis gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. [provided by RefSeq]
Related PathwayTranscription FactorsDruggable Genome Nucleotide excision repairUbiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate). A:293T. B:A431. 12% SDS PAGE. TA308479 diluted at 1:500
WB Image
ERCC8 antibody [N2C2], Internal detects ERCC8 protein by Western blot analysis. A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. D. 30 ug NIH-3T3 whole cell lysate/extract. E.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using ERCC8(CSA)(TA308479) antibody at 1:200 dilution.

 

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