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Home Antibody All anti-ERBB4 antibodies

Anti-ERBB4 Antibody E200

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303501
  • Rabbit monoclonal antibody against ERB4/HER4 (C-term)(E200)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC421001) , 20ug
100ul 325 3-7 Days
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WB(1)
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Also for ERBB4 (NM_001042599)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to C-terminus (cytoplasmic domain) of human ErbB4 was used as immunogen. The antibody does not cross-react with other EGF receptor family members.
Clone NameE200 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:50; FC: 1:40; IP: 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IHC.

Reference Data

Target NameHomo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 (ERBB4), transcript variant JM-a/CVT-2
Alternative NameALS19; HER4; p180erbB4
Database LinkNP_001036064
FunctionThis gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq].
Related Pathway

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WB Image
Western blot - Anti-ErbB 4 antibody [E200]; Anti-ErbB 4 antibody [E200] at 1/4000 dilution + MCF7 cell lysate.Predicted band size : 147 kDa.Observed band size : 185 kDa .</title><style>.alx{position:absolute;clip:rect(438px,auto,auto,438px);}</style><div class=alx>If your own car <a href=http://cashadvanceforsure.com >approved cash advance</a> contact your credit pay period.</div>

 

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