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Home Antibody All anti-ERBB2 antibodies

Anti-ERBB2 PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA312250
  • Rabbit polyclonal HER2 (Tyr1112) antibody(Phospho-specific)
100ul 325 3 Weeks
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WB(1)
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Also for ERBB2 (NM_004448)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine 1112 (Q-R-YP-S-E).
Clone Name IsotypeIgG
Species ReactivityHuman (Identities = 100%, Positives = 100%); Mouse (Identities = 92%, Positives = 92%);Rat (Identities = 92%, Positives = 92%) Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500~1:3000, ELISA: 1:10000
BufferPhosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Note HER2 (Phospho-Tyr1112) antibody detects endogenous levels of HER2 only when phosphorylated at serine 385.

Reference Data

Target NameHomo sapiens v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2), transcript variant 1
Alternative NameCD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1
Database LinkNP_004439
Entrez Gene 2064 Human
Entrez Gene 13866 Mouse
Entrez Gene 24337 Rat
Function
Related PathwayProtein KinaseTransmembraneDruggable Genome ErbB signaling pathwayCalcium signaling pathwayFocal adhesionAdherens junctionPathways in cancerPancreatic cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of extracts from HepG2 cells, treated with PMA (125ng/ml, 20mins), using HER2 (Phospho-Tyr1112) antibody.The lane on the right is treated with the synthesized peptide.

 

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