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Home Antibody All anti-EphB3 antibodies

Anti-EphB3 Antibody EPR8280

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310461
  • Rabbit Monoclonal antibody against EphB3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401410) , 20ug
100ul 325 3-7 Days
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WB(1)
IF(1)
Assay(1)
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Also for EphB3 (NM_004443)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain of human EphB3 was used as an immunogen.
Clone NameEPR8280 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P.

Reference Data

Target NameHomo sapiens EPH receptor B3 (EPHB3)
Alternative NameETK2; HEK2; TYRO6
Database LinkNP_004434
FunctionEphB3 is a receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional singnaling into neighboring cells. It plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. EphB3 controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. It also plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Eph receptor B3 antibody [EPR8280]; All lanes : Anti-Eph receptor B3 antibody [EPR8280] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : MOLT4 cell lysate.Lane 5 : NIH3T3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 110 kDa.
Assay Image
Other-Anti-Eph receptor B3 antibody [EPR8280](TA310461); Equilibrium disassociation constant (KD)..
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Eph receptor B3 antibody [EPR8280]; Immunocytochemical analysis of HeLa cells labelling Eph receptor B3 with TA310461 at 1/100.

 

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