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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-EphB3 antibodies

Anti-EphB3 Antibody EPR8280

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310461
  • Rabbit Monoclonal antibody against EphB3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401410) , 20ug
 100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IF(1)
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Also for EphB3 (NM_004443)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens EPH receptor B3 (EPHB3)
Synonyms:ETK2; HEK2; TYRO6
ImmunogenA synthetic peptide corresponding to residues in the extracellular domain of human EphB3 was used as an immunogen.
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone NameEPR8280 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1,000 - 10,000;
BackgroundEphB3 is a receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional singnaling into neighboring cells. It plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. EphB3 controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. It also plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt (1).
Related Pathway

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WB Image
Western blot analysis on (A) Jurkat, (B) HeLa, (C) HepG2, (D) Molt-4, and (E) NIH/3T3 cell lysates using anti-EphB3 RabMAb.
IF Image
Immunofluorescent staining of HeLa cells using anti-EphB3 RabMAb.

 

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