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Home Antibody All anti-EPAS1 antibodies

Anti-EPAS1 Antibody ep190b

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301435
  • Mouse Monoclonal Antibody against HIF-2 alpha (ep190b)
100ul 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenHuman HIF-2 alpha amino acids 535-631.
Clone Nameep190b IsotypeIgG1
Species Reactivityhuman, rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:500, IHC: 1: 150-1:300
BufferPBS and 0.1% sodium azide
Purification protein G purified

Reference Data

Target NameHomo sapiens endothelial PAS domain protein 1 (EPAS1)
Alternative NamebHLHe73; ECYT4; HIF2A; HLF; MOP2; PASD2
Database LinkNP_001421
FunctionHypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease. HIF-2 alpha is predominantly expressed in highly vascularized tissues of adult humans and endothelial cells of the embryonic and adult mouse, whereas HIF-1 alpha functions primarily in extravascular tissues. HIF-2 alpha is also a potent activator of the tie-2 gene, which is known to be selectively expressed in endothelial cells.
Related Pathway
Adipogenesis

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WB Image
HIF-2 alpha detected in hypoxic human lysate. Lane 1: normoxic A549 lysate control, lane 2: hypoxic A549 lysate
IHC Image
Staining of heart, cardiac myocytes

 

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