Home Antibody All anti-ENTPD3 antibodies
Also for ENTPD3 (NM_001248)
|T-cadherin antibody was raised against a 15 amino acid peptide from near the amino terminus of human T-cadherin.|
||ELISA, WB: 0.5 - 1 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens ectonucleoside triphosphate diphosphohydrolase 3 (ENTPD3), transcript variant 2|
|CD39L3; HB6; NTPDase-3|
Entrez Gene 956 Human
Entrez Gene 215446 Mouse
|T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth (1). T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage (2). T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers (3,4). Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation (5).|
|Transmembrane Purine metabolismPyrimidine metabolism|
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Western blot analysis of T-cadherin in 3T3 lysate with T-cadherin antibody at (A) 0.5 and (B) 1 ug/mL.
Immunofluorescence of T-cadherin in K562 cells with T-cadherin antibody at 20 ug/mL.