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Home Antibody All anti-ENC1 antibodies

Anti-ENC1 Antibody EPR5406(B)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310456
  • Rabbit Monoclonal antibody against ENC1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401201) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ENC1 was used as an immunogen.
Clone NameEPR5406(B) IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:50 - 1:100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens ectodermal-neural cortex 1 (with BTB domain) (ENC1), transcript variant 2
Alternative NameCCL28; ENC-1; KLHL35; KLHL37; NRPB; PIG10; TP53I10
Database LinkNP_001243503
FunctionDNA damage and/or hyperproliferative signals activate wild-type p53 tumor suppressor protein (TP53), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. ENC1 is a redox-controlling protein. Reactive oxygen species (ROS) are noted to be potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. ENC1 is also an actin-binding protein (1).
Related Pathway

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WB Image
Western blot - Anti-ENC1 antibody [EPR5406(B)]; Anti-ENC1 antibody [EPR5406(B)] at 1/1000 dilution + Human brain fetal lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 66 kDa.Observed band size : 66 kDa.
Assay Image
Other-Anti-ENC1 antibody [EPR5406(B)](TA310456); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ENC1 antibody [EPR5406(B)]; TA310456, at 1/100 dilution, staining ENC1 in paraffin-embedded Human brain tissue by Immunohistochemistry.

 

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