Anti-ENC1 Antibody, EPR5406(B)

Also for ENC1 (NM_001256574)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues in human ENC1 was used as an immunogen.
Clone Name	EPR5406(B)	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:50 - 100; ICC: 1:100 - 250;
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens ectodermal-neural cortex 1 (with BTB domain) (ENC1), transcript variant 2
Alternative Name	CCL28; ENC-1; KLHL35; KLHL37; NRPB; PIG10; TP53I10
Database Link	NP_001243503
Function	DNA damage and/or hyperproliferative signals activate wild-type p53 tumor suppressor protein (TP53), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. ENC1 is a redox-controlling protein. Reactive oxygen species (ROS) are noted to be potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. ENC1 is also an actin-binding protein (1).
Related Pathway

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WB Image

Western blot analysis on fetal brain lysate using anti-ENC1 RabMAb.

IHC Image

Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-ENC1 RabMAb.

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
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FITC
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DyLight® 594
DyLight® 633

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Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-ENC1 Antibody EPR5406(B)

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data