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Anti-ENC1 Antibody EPR5406(B)
Also for ENC1 (NM_001256574)
|A synthetic peptide corresponding to residues in human ENC1 was used as an immunogen.|
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC/IF: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for IP.
|Homo sapiens ectodermal-neural cortex 1 (with BTB domain) (ENC1), transcript variant 2|
|CCL28; ENC-1; KLHL35; KLHL37; NRPB; PIG10; TP53I10|
Entrez Gene 8507 Human
|DNA damage and/or hyperproliferative signals activate wild-type p53 tumor suppressor protein (TP53), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. ENC1 is a redox-controlling protein. Reactive oxygen species (ROS) are noted to be potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. ENC1 is also an actin-binding protein (1).|
|Druggable Genome |
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Western blot - Anti-ENC1 antibody [EPR5406(B)]; Anti-ENC1 antibody [EPR5406(B)] at 1/1000 dilution + Human brain fetal lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 66 kDa.Observed band size : 66 kDa.
Other-Anti-ENC1 antibody [EPR5406(B)](TA310456); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ENC1 antibody [EPR5406(B)]; TA310456, at 1/100 dilution, staining ENC1 in paraffin-embedded Human brain tissue by Immunohistochemistry.