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Home Antibody All anti-EIF6 antibodies

Anti-EIF6 Antibody EPR6513

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310452
  • Rabbit Monoclonal antibody against eIF-6 (EIF6)
100ul 325 3-7 Days
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WB(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human eIF-6 was used as an immunogen.
Clone NameEPR6513 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
Predicted MW Explanation 27 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens integrin beta 4 binding protein (ITGB4BP), transcript variant 3
Alternative NameCAB, EIF6, EIF3A, p27BBP, b(2)gcn
Database LinkNP_852134
Entrez Gene 3692 Human
Entrez Gene 16418 Mouse
Entrez Gene 305506 Rat
FunctionHemidesmosomes are structures that link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. eIF-6 binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. It is insoluble and found in both the nucleus and cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits (1).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Integrin beta 4 binding protein antibody [EPR6513]; All lanes : Anti-Integrin beta 4 binding protein antibody [EPR6513] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : K562 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 27 kDa.
Assay Image
Other-Anti-Integrin beta 4 binding protein antibody [EPR6513](TA310452); Equilibrium disassociation constant (KD)..

 

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