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Home Antibody All anti-EIF6 antibodies

Anti-EIF6 Antibody EPR6513

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310452
  • Rabbit Monoclonal antibody against eIF-6 (EIF6)
100ul $325 3-7 Days
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WB(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human eIF-6 was used as an immunogen.
Clone NameEPR6513 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens integrin beta 4 binding protein (ITGB4BP), transcript variant 3
Alternative NameCAB, EIF6, EIF3A, p27BBP, b(2)gcn
Database LinkNP_852134
FunctionHemidesmosomes are structures that link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. eIF-6 binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. It is insoluble and found in both the nucleus and cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits (1).
Related Pathway

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WB Image
Western blot - Anti-Integrin beta 4 binding protein antibody [EPR6513]; All lanes : Anti-Integrin beta 4 binding protein antibody [EPR6513] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : K562 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 27 kDa.
Assay Image
Other-Anti-Integrin beta 4 binding protein antibody [EPR6513](TA310452); Equilibrium disassociation constant (KD)..

 

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