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Anti-EIF6 Antibody EPR6513
Also for EIF6 (NM_181469)
|A synthetic peptide corresponding to residues near the C-terminus of human eIF-6 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens integrin beta 4 binding protein (ITGB4BP), transcript variant 3|
|CAB, EIF6, EIF3A, p27BBP, b(2)gcn|
|Hemidesmosomes are structures that link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. eIF-6 binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. It is insoluble and found in both the nucleus and cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits (1). |
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Western blot - Anti-Integrin beta 4 binding protein antibody [EPR6513]; All lanes : Anti-Integrin beta 4 binding protein antibody [EPR6513] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : K562 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 27 kDa.
Other-Anti-Integrin beta 4 binding protein antibody [EPR6513](ab133321); Equilibrium disassociation constant (KD)..