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Home Antibody All anti-EIF4EBP1 antibodies

Anti-EIF4EBP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA321620
  • Anti-EIF4EBP1 rabbit polyclonal antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401322) , 20ug Explanation
100ul 325 2-3 Weeks
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WB(1)
IHC(1)
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Also for EIF4EBP1 (NM_004095)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 4-118 amino acids of human eukaryotic translation initiation factor 4E binding protein 1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1.2mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:2000-5000, WB: 1:500-2000,IHC: 1:25-100
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1)
Alternative Name4E-BP1; 4EBP1; BP-1; PHAS-I
Database LinkNP_004086
Entrez Gene 1978 Human
Entrez Gene 13685 Mouse
Entrez Gene 116636 Rat
FunctionThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Related Pathway ErbB signaling pathwaymTOR signaling pathwayInsulin signaling pathwayAcute myeloid leukemia

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 13kDa. Positive control: 293T cell lysate. Recommended dilution: 1/500-2000. (Gel: 8+12%SDS-PAGE Lysate: 40 ug Primary antibody: 1/320 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 2 minutes)
IHC Image
Predicted cell location: Cytoplasm and Nucleus. Positive control: Human ovarian cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using EIF4EBP1 antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification:x200)

 

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