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Home Antibody All anti-EI24 antibodies

Anti-EI24 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319782 Rabbit Polyclonal EI24 Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenEI24 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human EI24.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 5 ug/mL
BufferEI24 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification EI24 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens etoposide induced 2.4 (EI24), transcript variant 1
Alternative NameEPG4; PIG8; TP53I8
Database LinkNP_004870
Entrez Gene 9538 Human
Entrez Gene 13663 Mouse
Entrez Gene 300514 Rat
FunctionEI24 Antibody: The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor. EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER). It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2. EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness. Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer.
Related PathwayTransmembraneDruggable Genome p53 signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of EI24 in rat liver tissue lysate with EI24 antibody at (A) 1 and (B) 2 ug/mL.

IHC Image
Immunohistochemistry of EI24 in rat liver tissue with EI24 antibody at 5 ug/mL.


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