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Home Antibody All anti-EHMT2 antibodies

Anti-EHMT2 Antibody EPR4018(2)

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307041 Rabbit monoclonal antibody against G9a(clone EPR4018(2)) 100ul $325 In Stock
LC410814 EHMT2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for EHMT2 (NM_025256)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human G9a was used as an immunogen.
Clone NameEPR4018(2) IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens euchromatic histone-lysine N-methyltransferase 2 (EHMT2), transcript variant 3
Alternative NameBAT8; C6orf30; G9A; GAT8; KMT1C; NG36
Database LinkNP_079532
Entrez Gene 10919 Human
FunctionG9a is a histone methyltransferase that preferentially methylates 'Lys-9' of histone H3 and 'Lys-27' of histone H3 (in vitro). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. G9a is probably targeted to histone H3 by different DNA-binding proteins (1). G9a is also required for the efficient repression of developmentally regulated genes during embryonic stem cell differentiation (2). It is localized in the nucleus, where it associates with euchromatic regions but not heterochromatin (1).
Related PathwayDruggable Genome Lysine degradation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-KMT1C / G9a antibody [EPR4018(2)]; All lanes : Anti-KMT1C / G9a antibody [EPR4018(2)] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 132 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KMT1C / G9a antibody [EPR4018(2)]; Immunohistochemical analysis of paraffin-embedded Human carcinoma of thyroid gland tissue labelling KMT1C / G9a with TA307041 at 1/50 dilution.
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