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Anti-EGFR TRUEMAB Antibody Clone 3H2
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for EGFR (NM_201283)
|Full length human recombinant protein of human EGFR(NP_958440) produced in HEK293T cell.|
|WB, IHC, IF
|| WB 1:4000, IHC 1:150, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 3|
|ERBB; ERBB1; HER1; mENA; PIG61|
|The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]. |
Cytokine-cytokine receptor interaction
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EGFR (RC214877, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EGFR.
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-EGFR mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA506224)
Anti-EGFR mouse monoclonal antibody (TA506224) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY EGFR(RC214877).