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Home Antibody All anti-EGFR antibodies

Anti-EGFR PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA322653
  • Anti-EGFR (phospho-Tyr1110) Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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WB(1)
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Also for EGFR (NM_005228)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide sequence around phosphorylation site of tyrosine 1110 (P-V-Y(p)-H-N) derived from Human EGFR.
Clone Name IsotypeIgG
Species ReactivityHuman; Mouse; Rat Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1000
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens epidermal growth factor receptor (EGFR), transcript variant 1
Alternative NameERBB; ERBB1; HER1; mENA; PIG61
Database LinkNP_005219
Entrez Gene 1956 Human
Entrez Gene 13649 Mouse
Entrez Gene 24329 Rat
FunctionReceptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayProtein KinaseSecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsDruggable Genome MAPK signaling pathwayErbB signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionEndocytosisDorso-ventral axis formationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 175 kDa . Positive control: HUVEC cells treated with EGF lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1: HUVEC cells untreated with EGF lysate Lane2: HUVEC cells treated with EGF lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)

 

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