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Home Antibody All anti-EGFR antibodies

Anti-EGFR PHOSPHO Antibody Y39

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303486
  • Rabbit monoclonal antibody against Phospho-EGFR (Py1086)(Y39) (phospho-specific)
100ul 325 3-7 Days
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WB(1)
IF(1)
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Also for EGFR (NM_005228)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Tyr1086 of human EGF receptor was used as immunogen. The antibody only detects EGFR phosphorylated on Tyrosine 1086 of the mature human isoform 1 (corresponding to Y1110 from the precursor
Clone NameY39 IsotypeWhole Cell Lysate
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:5000; ICC: 1:100 - 1:250; IP: 1:150
BufferDoes not react with Rat. Is unsuitable for Flow Cyt or IHC.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IHC.

Reference Data

Target NameHomo sapiens epidermal growth factor receptor (EGFR), transcript variant 1
Alternative NameERBB; ERBB1; HER1; mENA; PIG61
Database LinkNP_005219
FunctionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq].
Related Pathway
Adherens junction
Cytokine-cytokine receptor interaction
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
Focal Adhesion
MAPK signaling pathway

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WB Image
Western blot - EGFR (phospho Y1086) antibody [Y39]; All lanes : Anti-EGFR (phospho Y1086) antibody [Y39] at 1/10000 dilution.Lane 1 : Untreated A431 cell lysate.Lane 2 : A431 cell lysate treated with EGF.Predicted band size : 134 kDa.Observed band size : 150 kDa .
IF Image
Immunofluorescence - EGFR (phospho Y1086) antibody [Y39]; Immunofluorescent analysis of EGFR (phospho Y1086) expression in A431 cell culture, using 1/100 TA303486.

 

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