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Home Antibody All anti-EGFR antibodies

Anti-EGFR PHOSPHO Antibody Y38

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SKU Description Amount Price Availability*  
TA303485
  • Rabbit monoclonal antibody against Phospho-EGFR (pY1068)(Y38) (phospho-specific)
100ul $325 3-7 Days
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IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGF receptor was used as immunogen. The antibody only detects EGFR phosphorylated on Tyrosine 1068 of the mature human isoform 1 (corresponding to Y1092 from the precursor
Clone NameY38 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *IHC, IF Suggested DilutionsWB: 1:10000; ICC/IF: 1:100 - 1:250; IHC-P: Use at an assay dependent dilution; FC: 1:40; IP: 1:150
Predicted MW Explanation 135 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens epidermal growth factor receptor (EGFR), transcript variant 1
Alternative NameERBB; ERBB1; HER1; mENA; NISBD2; PIG61
Database LinkNP_005219
Entrez Gene 1956 Human
FunctionThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq].
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayProtein KinaseSecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsDruggable Genome MAPK signaling pathwayErbB signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionEndocytosisDorso-ventral axis formationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Immunohistochemistry (Paraffin-embedded sections) - EGFR (phospho Y1068) antibody [Y38]; Immunohistochemical analysis of the expression of EGF receptor phosphorilated at Tyrosine 1068 in paraffin embedded prostate cancer, using 1/50 TA303485.
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Immunocytochemistry/ Immunofluorescence - EGFR (phospho Y1068) antibody [Y38]; Immunofluorescent analysis of the expression of EGF receptor phosphorilated at Tyrosine 1068 in A431 cells, using 1/100 TA303485.
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