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Home Antibody All anti-EFHD2 antibodies

Anti-EFHD2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306945
  • Rabbit Polyclonal EFHD2 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411309) , 20ug
100ug $325 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for EFHD2 (NM_024329)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenEFHD2 antibody was raised against a 16 amino acid peptide near the amino terminus of human EFHD2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens EF-hand domain family, member D2 (EFHD2)
Alternative NameSWS1
Database LinkNP_077305
FunctionEFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-kappa-B-activating branch.
Related Pathway

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WB Image
Western blot analysis of EFHD2 in mouse brain tissue lysate with EFHD2 antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of EFHD2 in human brain tissue with EFHD2 antibody at 5 ug/mL.
IF Image
Immunofluorescence of EFHD2 in human brain tissue with EFHD2 antibody at 20 ug/mL.

 

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