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Anti-EFCAB4B Antibody Polyclonal
Also for EFCAB4B (NM_032680)
|EFCAB4B antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human EFCAB4B.|
||ELISA, WB: 1 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
|EFCAB4B Antibody is supplied in PBS containing 0.02% sodium azide.|
|EFCAB4B Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens EF-hand calcium binding domain 4B (EFCAB4B), transcript variant 3|
|EFCAB4B Antibody: EFCAB4B, also known as Calcium release-activated calcium channel regulator 2A, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation. EFCAB4B acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration. A closely related protein, EFCAB4A, is likely to play a similar role as EFCAB4B, but the detailed function of EFCAB4A is still under investigation. |
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Western blot analysis of EFCAB4B in mouse kidney tissue lysate with EFCAB4B antibody at 1 ug/mL.
Immunohistochemistry of EFCAB4B in human kidney tissue with EFCAB4B antibody at 10 ug/mL.