Home Antibody All anti-EED antibodies
|EED antibody was raised against an 18 amino acid peptide near the amino terminus of human EED.|
|Human, mouse, rat
||WB: 1-2 ug/ml, ELISA
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Affinity chromatography purified via peptide column
|Homo sapiens embryonic ectoderm development (EED), transcript variant 2|
Entrez Gene 8726 Human
Entrez Gene 13626 Mouse
Entrez Gene 293104 Rat
|The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and widely conserved polycomb group (PcG) family of proteins. The polycomb group (PcG) is a large and evolutionarily conserved set of genes whose products act in multimeric complexes to modify histones, which are then thought to cause stable and heritable states of transcriptional repression. EED shuttles between the nucleus and the plasma membrane and can interact with the cytoplasmic tail of integrin ß7 subunit. EED exerted an antiviral activity at the late stage of HIV-1 replication.|
|Transcription FactorsDruggable Genome |
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Western blot analysis of EED in human heart tissue lysate with Eed antibody at 1 µg/mL.