Home Antibody All anti-EED antibodies
|Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 229 of EED (Uniprot ID#O75530)|
|Human (Predicted: Mouse, Rat, Rhesus Monkey, Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)
|Homo sapiens embryonic ectoderm development (EED), transcript variant 2|
Entrez Gene 8726 Human
Entrez Gene 13626 Mouse
Entrez Gene 293104 Rat
Entrez Gene 703866 Monkey
|This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]|
|Transcription FactorsDruggable Genome |
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EED antibody detects EED protein by Western blot analysis. A. 30 ug H1299 whole cell lysate/extract. B. 30 ug HCT116 whole cell lysate/extract. 10 % SDS-PAGE. EED antibody (TA308744) dilution: 1:1000
Immunohistochemical analysis of paraffin-embedded SAS Xenograft, using EED(TA308744) antibody at 1:100 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed A431, using EED(TA308744) antibody at 1:500 dilution.