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Home Antibody All anti-ECE2 antibodies

Anti-ECE2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA323364
  • Anti-ECE2 Rabbit Polyclonal Antibody
100ul 325 2-3 Weeks
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IHC(2)

OriGene Data

ImmunogenFusion protein corresponding to a region derived from 25-235 amino acids of human endothelin converting enzyme 2
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *IHC Suggested DilutionsELISA: 1:2000-5000, IHC: 1:50-200
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens endothelin converting enzyme 2 (ECE2), transcript variant 3
Alternative NameKIAA0604; MGC17664; MGC2408; MGC78487
Database LinkNP_115707
Entrez Gene 9718 Human
Entrez Gene 107522 Mouse
Entrez Gene 408243 Rat
FunctionEndothelin-converting enzymes; such as ECE2 (EC 3.4.24.71); are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides; including neurotensin; angiotensin I; substance P; proenkephalin-derived peptides; and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Predicted cell location: Cytoplasm. Positive control: Human colon and gastric cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using ECE2 antibody at dilution 1/40, on the right is treated with the fusion protein. (Original magnification:x 200)
IHC Image
Predicted cell location: Cytoplasm. Positive control: Human colon and gastric cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using ECE2 antibody at dilution 1/40, on the right is treated with the fusion protein. (Original magnification:x200)

 

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