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Anti-Dlg2 Antibody S18-30


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA326525 Mouse Monoclonal Anti-Chapsyn-110 Antibody 100µg $325 3-7 Days
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OriGene Data

ImmunogenFusion protein amino acids 1-852 of rat Chapsyn-110;
Clone NameS18-30 IsotypeIgG1
Species ReactivityHuman (weak), Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB: 1-10ug/ml, IHC: 0.1-1.0ug/ml, IF: 1.0-10ug/ml
BufferPBS pH7.4, 50% glycerol
Purification Protein G Purified
Note Detects ~110kDa. No cross-reactivity against other MAGUK family members, PSD95, SAP97, SAP102, expressed in transfected cells.

Reference Data

Target NameRattus norvegicus discs, large homolog 2 (Drosophila) (Dlg2)
Alternative NameDlgh2
Database LinkNP_071618
Entrez Gene 1740 Human
Entrez Gene 23859 Mouse
Entrez Gene 64053 Rat
FunctionChapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80% identical to PSD-95/SAP90 and SAP97 . It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins .
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Chapsyn-110 in rat brain membrane lysates using a 1:1000 dilution of the antibody


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