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Home Antibody All anti-DYNC1LI1 antibodies

Anti-DYNC1LI1 TRUEMAB Antibody Clone OTI2B6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA501601 anti-DYNC1LI1 mouse monoclonal antibody, clone OTI2B6 (formerly 2B6) 100ul 325
In Stock
LC414168 DYNC1LI1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501601 Carrier-free (BSA/glycerol-free) DYNC1LI1 mouse monoclonal antibody, clone OTI2B6 (formerly 2B6) 100ug $450 3-4 weeks
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Also for DYNC1LI1 (NM_016141)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human DYNC1LI1 (NP_057225) produced in HEK293T cell.
Clone NameClone OTI2B6 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2000, IF 1:100, FLOW 1:100
Predicted MW Explanation 56.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens dynein, cytoplasmic 1, light intermediate chain 1 (DYNC1LI1)
Alternative NameDNCLI1; LIC1
Database LinkNP_057225
Entrez Gene 51143 Human
FunctionActs as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DYNC1LI1 (RC222010, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DYNC1LI1.

IF Image
Anti-DYNC1LI1 mouse monoclonal antibody (TA501601) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY DYNC1LI1(RC222010).

IF Image
Immunofluorescent staining of HeLa cells using anti-DYNC1LI1 mouse monoclonal antibody (TA501601).

FC Image
HEK293T cells transfected with either RC222010 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-DYNC1LI1 antibody(TA501601), and then analyzed by flow cytometry.


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