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Home Antibody All anti-DVL3 antibodies

Anti-DVL3 Antibody

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SKU Description Amount Price Availability*  
TA318951 Rabbit polyclonal anti-Dvl3 antibody 100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 583 of mouse Dvl3
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) peptide affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens dishevelled segment polarity protein 3 (DVL3)
Alternative NameKIAA0208
Database LinkNP_004414
Entrez Gene 1857 Human
Entrez Gene 13544 Mouse
Entrez Gene 303811 Rat
FunctionDvl1, Dvl2, and Dvl3 are mammalian homologs of Dsh (disheveled) proteins that are involved in Wnt signaling pathways. Upon treatment with Wnt proteins, Dvls become hyperphosphorylated and accumulate in the nucleus. Dvls have been reported to mediate endocytosis and may also play a role in certain cancers.
Related PathwayES Cell Differentiation/IPSDruggable Genome Wnt signaling pathwayNotch signaling pathwayMelanogenesisPathways in cancerColorectal cancerBasal cell carcinomaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Dvl3 in Jurkat cell lysate (Lane 1& 2) and 3T3 cell lysate (Lane 3).
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