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Home Antibody All anti-DSP antibodies

Anti-DSP Antibody EPR4383(2)

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310428
  • Rabbit Monoclonal antibody against Desmoplakin (DSP)
100ul $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Desmoplakin was used as an immunogen.
Clone NameEPR4383(2) IsotypeIgG
Species ReactivityRat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 332 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens desmoplakin (DSP), transcript variant 2
Alternative NameDCWHKTA; DP; DPI; DPII
Database LinkNP_001008844
Entrez Gene 1832 Human
Entrez Gene 306871 Rat
FunctionDesmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus (1).
Related PathwayDruggable Genome Arrhythmogenic right ventricular cardiomyopathy (ARVC)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Desmoplakin antibody [EPR4383(2)]; All lanes : Anti-Desmoplakin antibody [EPR4383(2)] at 1/1000 dilution.Lane 1 : A431 cell lysate.Lane 2 : HACAT cell lysate.Lane 3 : BXPC-3 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 332 kDa.
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Immunocytochemistry/ Immunofluorescence - Desmoplakin antibody [EPR4383(2)]; Immunofluorescent staining of Desmoplakin in A431 cells using TA310428 at 1/100 dilution.
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