Anti-DSG3 Antibody, EPR7420

Also for DSG3 (NM_001944)

Gene Name	Homo sapiens desmoglein 3 (DSG3)
Synonyms:	CDHF6; PVA
Immunogen	A synthetic peptide corresponding to residues in human DSG3 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR7420	Isotype
Species Reactivity	Human	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250; IP: 1:10 - 100; FC: 1:100 - 500;
Background	Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. DSG3 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris (1).
Related Pathway

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WB Image

Western blot analysis on (A) human tonsil and (B) A431 lysates using anti-DSG3 RabMAb.

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Anti-DSG3 Antibody EPR7420

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