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Home Antibody All anti-DSG1 antibodies

Anti-DSG1 Antibody EPR6766(B)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310426
  • Rabbit Monoclonal antibody against DSG1
100ul $325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues at the C-terminus of human DSG1 was used as an immunogen.
Clone NameEPR6766(B) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens desmoglein 1 (DSG1)
Alternative NameCDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1
Database LinkNP_001933
FunctionDesmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. DSG1 (Desmoglein 1) is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. DSG1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus (1).
Related Pathway

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WB Image
Western blot - Anti-Desmoglein 1 antibody [EPR6766(B)]; Anti-Desmoglein 1 antibody [EPR6766(B)] at 1/1000 dilution + Human skin lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 114 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Desmoglein 1 antibody [EPR6766(B)]; TA310426, at a 1/250 dilution, staining Desmoglein 1 in paraffin embedded Human skin tissue by Immunohistochemistry.

 

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