OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-DRAM antibodies

Anti-DRAM Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306390
  • Rabbit Polyclonal DRAM Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402672) , 20ug
100ug 325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)

OriGene Data

ImmunogenDRAM antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human DRAM.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens DNA-damage regulated autophagy modulator 1 (DRAM1)
Alternative NameDRAM
Database LinkNP_060840
FunctionDamage-regulated autophagy modulator (DRAM) is a p53 target gene encoding a lysosomal protein that induces autophagy, a process that degrades cytosolic proteins and organelles. It has been suggested that activation of DRAM by p53 is simultaneous to the activation by p53 of one or more proapoptotic genes such as PUMA, Bax, etc., and that the signaling pathways regulated by these genes promote a full cell death response. By itself, DRAM cannot induce apoptosis, but the fact that it is inactivated in certain cancers highlights the importance of DRAM and suggests that autophagy may play a more important role in cancer than initially suspected. At least two different isoforms of DRAM are known to exist.
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of DRAM in 293 cell lysate with DRAM antibody at (A) 0.5 and (B) 1 ug/ml.
IHC Image
Immunohistochemistry of DRAM in human liver tissue with DRAM antibody at 2.5 ug/ml.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title