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Home Antibody All anti-DPYSL3 antibodies

Anti-DPYSL3 Antibody EPR7593(B)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310421
  • Rabbit Monoclonal antibody against CRMP-4 (DPYSL3)
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for DPYSL3 (NM_001197294)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CRMP-4 was used as an immunogen.
Clone NameEPR7593(B) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens dihydropyrimidinase-like 3 (DPYSL3), transcript variant 1
Alternative NameCRMP-4; CRMP4; DRP-3; DRP3; LCRMP; ULIP; ULIP-1
Database LinkNP_001184223
FunctionCRMP-4 is a cytosolic phosphoprotein known to regulate cytoskeletal dynamics and is a known physiological substrate of GSK3. It has been shown to promote F-actin bundling. Furthermore, CRMP4, but not other CRMP family members, binds to RhoA, an important regulator of cell cycle progression and cytokinesis. These observations show that CRMP4 plays a role in regulating microtubule dynamics during mitosis (1). CRMP4 also influences neurite outgrowth (2). Thus, CRMP4 is involved in semaphorin-induced growth cone collapse and axonal guidance in developing neurons (3).
Related Pathway

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WB Image
Western blot - Anti-CRMP4 antibody [EPR7593(B)]; All lanes : Anti-CRMP4 antibody [EPR7593(B)] at 1/1000 dilution.Lane 1 : Human hippocampus lysate.Lane 2 : Human fetal brain lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 62 kDa.
Assay Image
Other-Anti-CRMP4 antibody [EPR7593(B)](TA310421); Equilibrium disassociation constant (KD)..

 

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