Anti-DPYSL3 Antibody, EPR7593(B)

Also for DPYSL3 (NM_001197294)

Gene Name	Homo sapiens dihydropyrimidinase-like 3 (DPYSL3), transcript variant 1
Synonyms:	CRMP-4; CRMP4; DRP-3; DRP3; LCRMP; ULIP; ULIP-1
Immunogen	A synthetic peptide corresponding to residues in human CRMP-4 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR7593(B)	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB	Suggested Dilutions	WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:50 - 100;
Background	CRMP-4 is a cytosolic phosphoprotein known to regulate cytoskeletal dynamics and is a known physiological substrate of GSK3. It has been shown to promote F-actin bundling. Furthermore, CRMP4, but not other CRMP family members, binds to RhoA, an important regulator of cell cycle progression and cytokinesis. These observations show that CRMP4 plays a role in regulating microtubule dynamics during mitosis (1). CRMP4 also influences neurite outgrowth (2). Thus, CRMP4 is involved in semaphorin-induced growth cone collapse and axonal guidance in developing neurons (3).
Related Pathway

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WB Image

Western blot analysis on (A) human hippocampus and (B) fetal brain lysates using anti-CRMP-4 RabMAb.

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Anti-DPYSL3 Antibody EPR7593(B)

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