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Home Antibody All anti-DPYD antibodies

Anti-DPYD Antibody EPR8811

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310417
  • Rabbit Monoclonal antibody against DPYD
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424917) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(2)
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Also for DPYD (NM_000110)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DPYD was used as an immunogen.
Clone NameEPR8811 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC/IF: 1:250 - 1:500
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant 1
Alternative NameDHP; DHPDHASE; DPD
Database LinkNP_000101
FunctionDPYD is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this protein result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy (1).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-DPYD antibody [EPR8811]; All lanes : Anti-DPYD antibody [EPR8811] at 1/1000 dilution.Lane 1 : Fetal kidney cell lysate.Lane 2 : THP1 cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 110 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DPYD antibody [EPR8811]; Immunohistochemical analysis of paraffin-embedded Human colon tissue staining DPYD with TA310417 at 1/250 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DPYD antibody [EPR8811]; Immunohistochemical analysis of paraffin-embedded Human lung tissue staining DPYD with TA310417 at 1/250 dilution.

 

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