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Home Antibody All anti-DPYD antibodies

Anti-DPYD Antibody EPR8811

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310417
  • Rabbit Monoclonal antibody against DPYD
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424917) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
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Also for DPYD (NM_000110)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human DPYD was used as an immunogen.
Clone NameEPR8811 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC/IF: 1:250 - 1:500
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant 1
Alternative NameDHP; DHPDHASE; DPD
Database LinkNP_000101
Entrez Gene 1806 Human
FunctionDPYD is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this protein result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy (1).
Related PathwayDruggable Genome Pyrimidine metabolismbeta-Alanine metabolismPantothenate and CoA biosynthesisDrug metabolism - other enzymesMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-DPYD antibody [EPR8811]; All lanes : Anti-DPYD antibody [EPR8811] at 1/1000 dilution.Lane 1 : Fetal kidney cell lysate.Lane 2 : THP1 cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat-anti-rabbit HRP at 1/2000 dilution.developed using the ECL technique.Predicted band size : 110 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DPYD antibody [EPR8811]; Immunohistochemical analysis of paraffin-embedded Human colon tissue staining DPYD with TA310417 at 1/250 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DPYD antibody [EPR8811]; Immunohistochemical analysis of paraffin-embedded Human lung tissue staining DPYD with TA310417 at 1/250 dilution.

 

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