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Home Antibody All anti-DPYD antibodies

Anti-DPYD Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308200
  • Rabbit polyclonal antibody to DPYD (dihydropyrimidine dehydrogenase)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424917) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for DPYD (NM_000110)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 174 of (Uniprot ID#Q12882)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.59mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens dihydropyrimidine dehydrogenase (DPYD), transcript variant 1
Alternative NameDHP; DHPDHASE; DPD
Database LinkNP_000101
Entrez Gene 1806 Human
FunctionThe protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. [provided by RefSeq]
Related PathwayDruggable Genome Pyrimidine metabolismbeta-Alanine metabolismPantothenate and CoA biosynthesisDrug metabolism - other enzymesMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Raji. B: K562. C: NCI-H929. 7.5% SDS PAGE. TA308200 diluted at 1:1000.
IHC Image
DPYD antibody [N1N2], N-term detects DPYD protein at cytoplasm on H358 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H358 xenograft. DPYD antibody [N1N2], N-term (TA308200) dilution: 1:500.

 

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