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Home Antibody All anti-DPAGT1 antibodies

Anti-DPAGT1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319635
  • Rabbit Polyclonal DPAGT1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419988) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for DPAGT1 (NM_001382)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenDPAGT1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human DPAGT1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferDPAGT1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification DPAGT1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (DPAGT1)
Alternative NameALG7; CDG-Ij; CDG1J; CMSTA2; D11S366; DGPT; DPAGT; DPAGT2; G1PT; GPT; UAGT; UGAT
Database LinkNP_001373
Entrez Gene 1798 Human
Entrez Gene 13478 Mouse
FunctionDPAGT1 Antibody: The UDP-N-acetylglucosamine-dolichyl-phosphate N-acetyl-glucosaminephosphotransferase (DPAGT1) is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. Mutations in this integral endoplasmic reticulum (ER) membrane protein enzyme belongs to the glycosyltransferase family 4 results in the congenital disorder of glycosylation type Ij with symptoms such as severe hypotonia, medically intractable seizures, mental retardation, microcephaly, and exotropia. Recent experiments have shown that DPAGT1 is a target of the Wnt/beta-catenin signaling pathway, with Wnt3a inducing higher DPAGT1 mRNA expression.
Related PathwayTransmembrane N-Glycan biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of DPAGT1 in mouse kidney tissue lysate with DPAGT1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IHC Image
Immunohistochemistry of DPAGT1 in human kidney tissue with DPAGT1 antibody at 2.5 ug/mL.
IF Image
Immunofluorescence of DPAGT1 in human kidney tissue with DPAGT1 antibody at 20 ug/mL.

 

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