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Anti-DOT1L TRUEMAB Antibody Clone OTI1F6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA802485 DOT1L mouse monoclonal antibody, clone OTI1F6 (formerly 1F6) 100ul 325
In Stock
LC410109 DOT1L HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF802485 Carrier-free (BSA/glycerol-free) DOT1L mouse monoclonal antibody, clone OTI1F6 (formerly 1F6) 100ug $450 3 Days
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-434 of human DOT1L (NP_115871) produced in E.coli.
Clone NameClone OTI1F6 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:500,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens DOT1-like histone H3K79 methyltransferase (DOT1L)
Alternative NameDOT1; KMT4
Database LinkNP_115871
Entrez Gene 84444 Human
FunctionThe protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011].
Related PathwayDruggable Genome Lysine degradation

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DOT1L (RC218547, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DOT1L.


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